Loupe · 会话式数字病理副驾驶 / Conversational Pathology Copilot

亮点 / Why Loupe

四个让病理医生留下来的理由Four reasons pathologists stay

会话即工作流Chat is the workflow用自然语言提问，得到带工具调用痕迹的可核查回答。Ask in plain language; get answers backed by a visible tool trace.
可核查的量化Verifiable quantificationIHC 阳性率、H-score、鉴别诊断与 PubMed 引用，就地呈现。IHC positivity, H-score, differential & PubMed — rendered inline.
智能体 + 人审Agents, human-approved智能体批量产出草稿，你逐条接受/驳回，预算与审计可控。Agents batch-draft; you accept/reject, with budgets & audit.
可治理Governable采纳率遥测、成本与审批率，部署可被量化与优化。Adoption telemetry, cost & approval rate — measurable, tunable.

业务流 / How a case moves through Loupe

从切片接入到出报告，一条贯穿的工作流One workflow, from slide intake to sign-out

Loupe 不是一堆零散功能，而是顺着真实诊断流程把 AI 嵌进每一步——而决定权始终在病理医生手里。Loupe isn’t a bag of features — it threads AI through the real diagnostic flow, with the pathologist deciding at every step.

01 接入与预读分诊 / Ingest & triage

切片入库，即被 AI 预读一遍Every slide is pre-read the moment it lands

上传或从 DICOMweb 导入全切片影像。Loupe 自动算出质控评分、写出一段“镜下预读”，并按器官归类——让你从最该看的切片开始。Upload or import WSIs via DICOMweb. Loupe scores QC, writes a scan-time pre-read, and groups by organ — so you start with the slide that matters.

02 会话式阅片 / Conversational read-out

问一句，得到可核查的答案Ask in plain language, get an auditable answer

选区直接提问。Loupe 调用工具读取该区域、做组织/细胞统计、量化 IHC（如 ER 92%、H-score 285）、检索 PubMed，并摆出它考虑过的鉴别诊断——不是只给结论。Select a region and ask. Loupe reads the tile, computes stats, quantifies IHC (e.g. ER 92%, H-score 285), cites PubMed, and shows the differential it weighed — not just a verdict.

03 自主智能体批处理 / Autonomous agents

一句话下达任务，智能体自己跑One sentence in, drafts out

“标出所有侵袭性肿瘤前沿并标记出芽灶”——智能体在迭代/时长/Token 预算内自主规划执行，逐张切片产出标注草稿，可对整组切片一键派发。“Map every invasive front and flag tumor budding.” The agent plans and runs within iteration / time / token budgets, drafting annotations per slide — dispatch across a whole case at once.

04 人审采纳 / Human review & adopt

AI 提草稿，你来定夺AI proposes, you decide

任务详情展示分步计划、预算用量与活动轨迹；草稿队列可逐条或批量接受/驳回，校验器把低置信项顶到队首；驳回理由进入下一轮提示。The task page shows the plan, budgets and activity trace; accept/reject drafts singly or in bulk, with a verifier surfacing low-confidence ones — and your reasons feed the next run.

task detail · plan, activity, draft review

05 多切片对比 / Compare in sync

H&E 与 IHC，并排同步阅读H&E and IHC, side by side, in sync

把同一病例的多张切片（H&E + MMR PMS2/MSH6，或 H&E + ER）放进同步缩放平移的对比视图——例如本例 MSH6 缺失提示错配修复缺陷、需 Lynch 筛查。Put a case’s slides (H&E + MMR PMS2/MSH6, or H&E + ER) into a pan/zoom-synced comparison — here MSH6 loss flags mismatch-repair deficiency for Lynch workup.

06 遥测与治理 / Telemetry & governance

“医生到底信不信 AI”——用数据回答Quantify whether clinicians actually trust the AI

跟踪分类器采纳率随置信度与时间的走势、按标签的接受情况，以及智能体的成本与审批率——让整个部署可被治理、可被优化。Track classifier adoption by confidence and over time, per-label acceptance, and agent cost & approval rate — so the whole deployment can be governed and tuned.

版本与部署 / Editions & deploy

同一套代码，两种版本，处处可部署One codebase, two editions, deploy anywhere

FastAPI + SQLAlchemy 异步后端、React 19 + OpenSeadragon 前端、OpenSlide 切片管线、可插拔多 LLM；提供 Docker / GPU / HTTPS 反代与 DICOMweb 导入。Async FastAPI + SQLAlchemy, React 19 + OpenSeadragon, OpenSlide pipeline, pluggable multi-LLM; Docker / GPU / HTTPS deploys and DICOMweb import.

能力 / Capability	Commercial 商业版	Education 教育版
会话阅片 · 标注 · 报告草稿Chat read-out · annotations · report draft	✓	✓
自主智能体 · 遥测 · 多切片对比Agents · telemetry · comparison	✓	✓
病理基础模型 UNI / CONCHPathology foundation models UNI / CONCH	—	✓ (CC-BY-NC-ND)
相似瓦片检索Similar-tile search	颜色纹理指纹color/texture fingerprint	✓ UNI embeddings
镜像 / 适用场景Image / use	最小镜像 · 云端可商用smallest · cloud-defensible	含权重 · 仅非商业科研教学weights baked · non-commercial

多 LLM 可插拔Pluggable LLMs

Gemini / OpenAI / MiniMax / Kimi 经统一兼容层接入。Gemini / OpenAI / MiniMax / Kimi via one compatible layer.

安全与审计Security & audit

JWT 鉴权、登录限流、全量审计事件、HTTPS 反代。JWT auth, rate-limit, full audit log, TLS proxy.

开放切片生态Open WSI ecosystem

OpenSlide 多厂商格式 · DZI 瓦片 · DICOMweb 导入。OpenSlide formats · DZI tiles · DICOMweb import.

把显微镜
变成一场对话Turn the microscope
into a conversation.